carbamazepine will lower the extent or influence of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
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The advised dosage of PROVIGIL for people with narcolepsy or OSA is two hundred mg taken orally at the time per day as an individual dose each morning.
Modafinil may be behavior-forming. Never ever share Provigil with A further person, Primarily somebody which has a heritage of drug abuse or dependancy. Keep the medication in an area exactly where Other folks are unable to reach it. Selling or giving away this drugs is versus the regulation.
It’s easier to break a a hundred mg tablet in 50 % than it really is to break a two hundred mg in fourths. The producer usually can make a crease down the middle to aid consumers split the tablets in 50 % evenly.
The encouraged dosage of PROVIGIL for sufferers with SWD is 200 mg taken orally at the time daily as an individual dose around one hour prior to the beginning in their perform shift.
Metabolism: Modafinil undergoes hepatic metabolism by using numerous pathways, which include CYP3A4. eighty% of the dose is recovered inside the urine in the shape of metabolites.
PROVIGIL is contraindicated in sufferers with regarded hypersensitivity to modafinil or armodafinil or its inactive ingredients [see WARNINGS AND PRECAUTIONS].
Drug Interactions Despite the fact that selected medicines should not be utilised alongside one another whatsoever, in other situations two distinctive medicines might be employed together regardless of whether an conversation could possibly happen. In these situations, your physician will want to alter the dose, or other safety measures may very well be essential.
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Just about every capsule-formed, white to off white pill is debossed with “PROVIGIL” on one particular side and “100 MG” on the other.
It's not necessarily identified no matter whether this medication will harm an unborn little one. Convey to your doctor In case you are Expecting or prepare to be pregnant.
Blood levels of cyclosporine could be lessened when made use of with PROVIGIL. Checking of circulating cyclosporine concentrations read more and suitable dosage adjustment for cyclosporine really should be deemed when employed concomitantly with PROVIGIL.
For the reason that clinical trials are done beneath greatly various disorders, adverse reaction fees observed during the medical trials of the drug cannot be specifically when compared with rates while in the scientific trials of Yet another drug and could not reflect the charges noticed in practice.